Combining tractography and cortical measures to test system-specific hypotheses in multiple sclerosis
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منابع مشابه
Combining tractography and cortical measures to test system-specific hypotheses in multiple sclerosis
The objective was to test three motor system-specific hypotheses in multiple sclerosis patients: (i) corticospinal tract and primary motor cortex imaging measures differ between multiple sclerosis patients and controls; (ii) in patients, these measures correlate with disability; (iii) in patients, corticospinal tract measures correlate with measures of the ipsilateral primary motor cortex. Elev...
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Disease-specific molecular events in cortical multiple sclerosis lesions
Cortical lesions constitute an important part of multiple sclerosis pathology. Although inflammation appears to play a role in their formation, the mechanisms leading to demyelination and neurodegeneration are poorly understood. We aimed to identify some of these mechanisms by combining gene expression studies with neuropathological analysis. In our study, we showed that the combination of infl...
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Cortical deafness in a patient with multiple sclerosis is reported. Complete recovery from total deafness was seen following stages of auditory agnosia and pure word deafness. The otological and neurophysiological studies suggested lesions in subcortical white matter. This report stresses the rarity of the condition, its subcortical origin and good prognosis.
متن کاملCortical relapses in multiple sclerosis.
BACKGROUND Multiple sclerosis (MS) is a white and grey matter disease of the central nervous system (CNS). It is recognized that cortical damage (i.e. focal lesions and atrophy) plays a role in determining the accumulation of physical and cognitive disability that is observed in patients with progressive MS. To date, an association of cortical lesions with clinical relapses has not been describ...
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ژورنال
عنوان ژورنال: Multiple Sclerosis Journal
سال: 2010
ISSN: 1352-4585,1477-0970
DOI: 10.1177/1352458510362440